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City XI presented by Hays: Ederson, Walker, Stones, Laporte, Mendy, Fernandinho, Bernardo, Mahrez, Silva (c), Sterling, Agüero
Subs: Muric, Kompany, De Bruyne, Sané, Otamendi, Jesus, Foden
Follow live: Spurs v Man City match day centre
The team selected looks like a powerful four-five-one on paper, with right-back Walker restored to the starting line-up for the first time since picking up a knock on international duty earlier this month. In-form centre-back Aymeric Laporte continues his ever-present record for the season.
In midfield, boss Pep Guardiola has gone with the Bernardo-David Silva nexus, with De Bruyne on the bench following his first start after injury last week against Shakhtar Donetsk. Fernandinho is set to pick up the anchor role, with Riyad Mahrez and Sterling providing width, the latter notching a league milestone.
In attack Sergio Aguero leads the line looking for his 150th Premier League goal.
READ: Spurs v City: TV info
City have only conceded once in the last seven matches - another clean sheet would be a new best under Pep Guardiola.
City are unbeaten in six Premier League away matches in London (W5 D1) and have won the last four in a row. We could now become the first non-London side to win five consecutive PL matches in the capital.
Follow the match on mancity.com
A look ahead to everything going on this week...