Pep Guardiola's men lock horns with Crystal Palace on Monday 14 March, with kick-off scheduled for 20:00 (UK).
The boss has described every game from now until the end of the campaign as a 'cup final', and with Liverpool hot on our heels at the Premier League summit, another victory could be crucial in this season's title race.
City currently sit three points clear at the top of the table, but will need to be at our best to maintain our impressive away form, with our only defeat on the road this season coming on the opening day.
Patrick Vieira's side have won three of their last four matches, and also claimed victory in October's reverse fixture at the Etihad Stadium.
It leaves FPL managers with some difficult selection decisions ahead of Saturday's 11:00 (UK) deadline, but rest assured the Scout is on hand to ease those worries as always.
Check out the latest FPL Scout Report below...
Phil Foden’s (£7.9m) away form can pose big problems for Crystal Palace in Gameweek 29 of Fantasy Premier League.
The Manchester City midfielder has scored against Brentford, Norwich City and Everton in his last four road trips, amassing 28 points.
Indeed, his total of six away goals ranks joint-second among all players in 2021/22.
The underlying numbers show Foden’s major all-round contribution on his travels.
Away from home, his 22 shots in the box and 13 shots on target are both more than any team-mate.
And his total of six big chances created on the road also place top for Pep Guardiola’s side.
Opponent to watch
Connor Gallagher (£6.2m) boasts the main attacking threat for the hosts, the midfielder having produced a goal, an assist and 13 points at the Etihad Stadium earlier this season.
Key man: With 121 points, Gallagher is Crystal Palace's highest scoring player in FPL so far this season. He also ranks ninth among his fellow midfielders across the Premier League.
Other Premier League pick
Elsewhere, Mohamed Salah (£13.2m) and Harry Kane (£12.3m) look set to go head-to-head for the captaincy, with both playing twice in Gameweek 29.
Liverpool’s Salah travels to Brighton & Hove Albion and Arsenal – away from home, his 10 goals and 19 big chances are both league-leading totals.
Kane visits Manchester United and Brighton on the back of three double-figure hauls in his last four outings.