La Albiceleste beat Venezuela 2-0 in Friday evening’s quarterfinal to book a clash with host nation Brazil and set up a game known as the ‘Battle of the South Americans’ at the Estádio Governador Magalhães Pinto Stadium in Belo Horizonte.
Inter Milan striker Lautaro Martinez scored after 10 minutes, with City legend Sergio Aguero providing the assist.
Real Betis midfielder Giovani Lo Celso wrapped up the victory on 74 minutes, just two minutes after coming on as a substitute.
In an ill-tempered first-half, five players were booked in the balmy Maracana Stadium in Rio.
Nicolas Otamendi had another solid game as Argentina look to win the competition for the first time in 26 years.
Both City stars played the full 90 minutes,
It will be the 111th meeting between the two rival nations, with Brazil winning 40 and Argentina making 38.
Aguero won his 94th cap this evening and Otamendi his 64th and the City duo will face team-mates Gabriel Jesus and, if he returns to fitness, Fernandinho.
Ederson is yet to be selected by Brazil boss Tite in this tournament.