City make eight changes from the side that beat Huddersfield Town on Sunday.
Benjamin Mendy is named a substitute after several weeks out.
The Blues include several Academy graduates in the 18-man squad and Ian Carlo Poveda makes his first senior appearance.
Philippe Sandler makes his first start after one appearance from the bench.
Pep Guardiola may also look to blood one or two of the youngsters during the course of the game.
Starting XI and bench
Muric, Danilo, Zinchenko, Delph, Garcia, Sandler, Foden, De Bruyne, Mahrez, Poveda, Aguero (c)
Subs: Grimshaw, Stones, Mendy, Jesus, F Nmecha, Bolton, Richards
As we’ve seen throughout the campaign, the Blues have a system that works extremely well and no matter what the personnel or the age group, the style and thinking is still the same.
So, we should expect the same slick passing game, press and 4-3-3 formation.
Fabian Delph is likely to take the anchor midfield role alongside Phil Foden and De Bruyne while Mahrez and Poveda will play on either flank of skipper Aguero.
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More minutes for senior stars
De Bruyne, Danilo and Aguero will all continue to gather vital match fitness minutes this evening.
Danilo’s form means he keeps his place at right-back, though has missed much of the campaign with injury.
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