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Pep Guardiola has made eight changes to his starting XI as City hunt down yet more Premier League records.
Bravo, Danilo, Kompany, Laporte, Zinchenko, Fernandinho, Yaya Toure, Gundogan, Sane, Bernardo, Jesus
Subs: Ederson, Foden, Diaz, Nmecha, De Bruyne, Mendy, Adarabioyo
Given the Blues weren’t at their best against Huddersfield, Pep has rung the changes with Claudio Bravo making his first Premier League start this season.
Oleksandr Zinchenko also returns, making his first appearance for almost two months.
David Silva, Raheem Sterling, Kyle Walker, Nicolas Otamendi, Fabian Delph and John Stones are all rested, while Sergio Aguero remains side-lined with injury.
Expect an emotional evening as Blues legend Yaya Toure makes his last home appearance for the Club.
The Ivorian will leave City at the end of the season, bringing an end to a magnificent eight-year stint in sky blue.
Yaya will skipper the side against the Seagulls and there will be a special presentation at the end of the game.
Records to tumble?
City can still become the first Premier League team in history to reach 100 points with victories over Brighton and Southampton.
A win this evening would set a new Premier League points record, and two goals would set a new goals scored record and most wins in a campaign.
The last time...
Stats and facts
This is the first league meeting between City and Brighton in Manchester for 30 years – the Blues won that meeting at Maine Road 2-1 with goals from Ian Brightwell and Paul Moulden.
Brighton haven’t fared well in Manchester over the years and have failed to win any of their last 17 games in the city against City or United
Brighton are looking to record three consecutive clean sheets in the top-flight for the first time since January 1982.
One worrying fact is that 41% of Pep Guardiola’s defeats as Man City manager have come on a Wednesday (7 of 17)!
Kick-off time, team news and TV information...