City go into the game on the back of a fine win away at Leicester on Saturday, a result which maintained out 14-point advantage at the top of the Premier League table.
Dortmund, meanwhile, lost at home in the Bundesliga to Eintracht Frankfurt.
We will have full coverage of Tuesday's game right here on ManCity.com.
Join us from 6pm for live minute-by-minute text updates on our Matchday Centre.
And then at 6.55pm, our We're Not Really Here live show gets under way, with Paul Dickov and Andy Morrison our guests in the studio.
We'll have short highlights at 11pm - and CITY+ subscribers can watch a full 90-minute replay from midnight.
Watch the press conference in full via the video above!