City host United on Sunday 11 December, with kick-off scheduled for 12:30 (UK).
It sees two of the Barclays Women's Super League's frontrunners lock horns in what could be hugely significant for both teams' title ambitions.
BARCLAYS WSL ETIHAD DERBY: GET YOUR TICKETS
City and United boast nine members of the victorious England side from Euro 2022, and are both within touching distance of the WSL summit ahead of the encounter.
We first welcomed our rivals to the Etihad Stadium in September 2019, with a Caroline Weir wonder strike enough to seal a 1-0 victory.
Over 31,213 were in attendance that day, a figure which remains a Club record crowd for a Women's fixture.
However, an even larger crowd is expected in the latest showdown as Gareth Taylor's side look to continue our incredible recent run of form.
With the World Cup currently taking place in Qatar - it's the next opportunity for City fans to get your football fix at the Etihad!
Tickets are selling fast, so make sure to get yours as soon as possible!
You can secure yours online by visiting: www.mancity.com/tickets/womens or by calling: +44 (0)161 444 1894.