The latest chapter in the saga comes on Sunday 11 December in the Barclays Women's Super League.
Over 40,000 tickets have already been snapped up for what promises to be a captivating encounter.
But there's plenty more than local bragging rights at stake in this weekend's 12:30 (UK) kick-off, with three points for either side of potentially huge significance in the WSL title race.
The trio have each played a huge role in our impressive run of form, which currently stands at eight successive victories in all competitions.
Having made the switch from Atletico Madrid and Barcelona respectively this summer, they have all enjoyed a swift transition into their new surroundings.
And ahead of Sunday's showdown, our Club photographers Tom Flathers and Declan Lloyd took them along to the Metrolink depot to sample an iconic Manchester sight - the tram!
Check out the best images from the shoot via the gallery below...