Kick-off is scheduled for 12:30 (UK) on Saturday 17 September, with Pep Guardiola's men knowing victory would move us top of the table for 24 hours at least.
We enter the tie on the back of a dramatic turnaround against Borussia Dortmund in the UEFA Champions League, with late strikes from John Stones and Erling Haaland seeing us run out 2-1 winners at the Etihad Stadium.
But another three points this weekend is far from a foregone conclusion, with Wolves aiming to build on their first victory of the season in their most recent outing.
Bruno Lage's side possess one of the toughest defences to crack in the Premier League, with their tally of just four conceded so far this season the best in the English top flight after six matches.
City will have our work cut out at Molineux, leaving FPL managers with some difficult selection decisions ahead of Friday's 18:30 deadline.
Thankfully, the Scout is on hand to provide the latest stats and advice on this weekend's fixtures.
Check out the latest FPL Scout Report below...
Bernardo Silva (£7.0m) has the form to prove decisive in Gameweek 8 of Fantasy Premier League.
The Portuguese has amassed 31 points from Gameweek 3 onwards, second only to the 49 points of Erling Haaland (£12.0m) for the champions.
Silva has combined two goals with two assists and five bonus points in that run, including his season-high haul of 13 points away to Newcastle United.
The underlying numbers show Silva’s all-round influence on Pep Guardiola’s attack.
His four shots in the box and eight chances created both place among the top three players for Man City during that spell.
Opponent to watch
Daniel Podence (£5.5m) is the hosts’ form player for Saturday lunchtime’s encounter at Molineux, having scored two of Wolves’ three goals this season.
The winger was named in the Gameweek Six Team of the Week after grabbing the winner in a 1-0 win over Southampton, and has already equalled his goal tally from 2021/22.
Elsewhere, Newcastle United forward Alexander Isak (£7.0m) and Southampton playmaker James Ward-Prowse (£6.5m) can thrive as differentials for the reduced round of matches.
Isak entertains a Bournemouth side who have conceded 15 goals in their three away fixtures.
Ward-Prowse has averaged 6.0 points per away match ahead of his visit to Aston Villa.