The League One outfit booked their place in the third round thanks to penalty shootout victories over Exeter City and Stevenage.
Our last clash with Gareth Ainsworth's side came during our Second Division promotion campaign, when the visitors ran out 2-1 winners at Maine Road in April 1999.
Wycombe currently sit second in League One, having won three of their opening four matches as they aim for an immediate return to the Championship.
City, along with the six other English sides to qualify for Europe this season, enter the competition at the third round stage as we set our sights on claiming the trophy for a record fifth successive year.
A ninth League Cup triumph would also see Pep Guardiola's men surpass Liverpool as the most successful side in the tournament's history.
Our third round clash is set to take place on the week commencing 20 September, with dates and times to be confirmed in due course.
Third-round draw in full
QPR v Everton
Preston v Cheltenham
Manchester United v West Ham United
Fulham v Leeds United
Brentford v Oldham Athletic
Watford v Stoke City
Chelsea v Aston Villa
Wigan Athletic v Sunderland
Norwich City v Liverpool
Burnley v Rochdale
Arsenal v AFC Wimbledon
Sheffield United v Southampton
Manchester City v Wycombe Wanderers
Millwall v Leicester City
Wolverhampton Wanderers v Tottenham Hotspur
Brighton & Hove Albion v Swansea City
Manchester City v Wycombe
Keep across mancity.com and our official app for essential pre-match information, including ticket updates, team news and previews from Pep Guardiola.
You can also get in the matchday mood as we kick-off our defence of the Carabao Cup title by tuning in to our live pre-match show one hour before kick-off, available on all digital platforms.
Matchday Live is a must-watch for any City supporter who enjoys their buildup, half-time and post-match coverage to take a particular focus on Pep Guardiola’s men.
Expert insight is provided by a guest panel of Manchester City legends, as well as plenty of humour along the way as we guide you through proceedings with a City-centric twist.
The show is also available to view in our Matchday Centre on mancity.com and our official app, providing minute-by-minute coverage of all the action, as well as unique pieces of insight, stats and reaction.
For those who miss the match, or just want to relive it, then a full-match replay will also be available from midnight with a CITY+ subscription.
More information on how to subscribe, as well as other benefits signing up entails, are available to view here.