City have won on 57 occasions, with United victorious 77 times. The two sides could not be separated in 53 of the previous 187 matches.
The first competitive meeting between the sides came in 1891 in the first qualifying round of the FA Cup. City were then called Ardwick AFC and Manchester United went by the name of Newton Heath.
Newton Heath won 5-1 at their North Road ground.
As this was a qualifying round of the FA Cup, some organisations do not include it in their records.
However, this weekend’s match will be considered the 188th competitive meeting between the two clubs on all Manchester City channels.