We welcome Marcelo Bielsa's men to the Etihad Stadium for a 20:00 (UK) kick-off this evening.
City have our sights set on claiming a seventh successive Premier League triumph, but know we'll need to be at our best to make that a reality against Tuesday's opponents.
Leeds came away from the Etihad Stadium with a smash and grab victory in last season's encounter and, while they are missing key players in Kalvin Phillips and Patrick Bamford, will still pose a serious threat to Guardiola's men.
It leaves FPL managers with plenty to ponder ahead of Tuesday's 18:15 transfer deadline but, as always, the Scout is on hand to help ease those difficult decisions.
Check out the latest FPL Scout Report below...
Raheem Sterling (£10.6m) welcomes Leeds United in his best form of 2021/22 Fantasy Premier League.
The City winger has scored in back-to-back matches for the first time this season, netting a penalty winner against Wolverhampton Wanderers last weekend.
Indeed, Sterling has blanked in just one of the last five Gameweeks, totalling 34 points thanks to three goals and an assist.
He has created 16 chances in the last four Gameweeks, more than any other player in FPL.
Furthermore, his 11 shots and six shots on target both ranked among the top two players for Pep Guardiola’s side in that period.
Opponent to watch
Leeds visit the Etihad Stadium in poor away form, with just a single clean sheet on their travels this term.
However, Raphinha (£6.6m) boasts the main danger for Marcelo Bielsa’s side, with four goals and an assist in his last six appearances.
Other Premier League pick
Elsewhere, Mohamed Salah (£13.1m) and Mason Mount (£7.6m) are among the top captain picks for Gameweek 17.
Liverpool’s Salah has scored in all four of his home meetings with Newcastle United, picking up 38 points.
Chelsea’s Mount entertains Everton off the back of three goals, two assists and 31 points in the last three Gameweeks.