The fixture at the Etihad Stadium will be shown live in the UK on BBC One and BBC iPlayer.
Our game is one of six to be aired on UK television between 6-9 January.
It will also be our second meeting with Chelsea in just four days after we face off in London in the Premier League on Thursday 5 January.
View all 2022/23 fixtures here
This tie marks the start of a new FA Cup campaign for City, with all Premier League clubs joining at this stage.
Pep Guardiola will this season be seeking to lift the famous trophy for a second time after a 6-0 win over Watford in the 2018/19 final.
We have already met the Stamford Bridge side in the Carabao Cup this season, recording a 2-0 win over Graham Potter's side in November.
We have met twice in the FA Cup semi-finals in the past decade. Chelsea won 1-0 in 2021 but City recorded a 2-1 win at Wembley in 2013.
All fixtures on UK television are as follows:
FRIDAY 6 JANUARY 2023
• Manchester United v Everton at 20:00 on ITV1, ITVX, UTV, STV and STV Player
SATURDAY 7 JANUARY 2023
• Sheffield Wednesday v Newcastle United at 18:00 on BBC One and BBC iPlayer
• Liverpool v Wolverhampton Wanderers at 20:00 on ITV4 and ITVX
SUNDAY 8 JANUARY 2023
• Cardiff City v Leeds United at 14:00 on ITV1, ITVX, UTV, STV and STV Player
• Manchester City v Chelsea at 16:30 on BBC One and BBC iPlayer
MONDAY 9 JANUARY 2023
• Oxford United v Arsenal at 20:00 on ITV1, ITVX, UTV, STV and STV Player
MAN CITY APP
As with all first-team matches, there will be comprehensive coverage on the official Man City app.
Two hours before kick off, our Matchday Centre will begin providing live text updates, gathering together all the latest team news, stats, analysis and quotes.
And then just before the teams are announced, Matchday Live will begin, with former City players joining us in the studio to offer their insight.
CITY+ subscribers can also watch a full 90-minute replay of every single game from midnight.
Stay tuned for any further fixture changes.