John Stones and Fabian Delph have been forced to withdraw from the England squad, while Nicolas Otamendi has pulled out of the Argentina squad.
Stones missed the Blues' 3-2 win at Swansea at the weekend and last played in the 1-0 win at Bournemouth where he came off with a muscle issue.
Delph played against the Swans but came off in the second-half of the game at The Liberty Stadium.
Otamendi has also been pulled out of the Argentina squad with what is believed to be a minor knock.
Chelsea's Ruben Loftus-Cheek has also withdrawn from the squad and James Ward-Prowse of Southampton has been called up.