The mid-table League Two side claimed another notable scalp as they saw off Tony Pulis’ Middlesbrough 2-0 at Rodney Parade in their FA Cup fourth round replay to set up a tie with the Premier League champions.
Second-half goals from Robbie Willmott and Padraig Amond sent the home fans wild as The Exiles made it to the last 16 for the first time in exactly 70 years.
Now Newport, who sit 80 places below the Blues in the league pyramid, will host Pep Guardiola’s title-chasing City in a tie that conjures up the magic of the FA Cup.
Mike Flynn's battlers are unbeaten in their last five home FA Cup ties against teams from higher divisions.
The Blues have never played at Rodney Parade – the only two previous game away to Newport were played at their former home, Somerton Park.
The only two league meetings between the teams took place in 1946/47, with the Blues winning 3-0 at Somerton Park and, in City’s latest finish to a season ever, the Blues won 5-1 at Maine Road in the return on 14 June, 1947.
The last meeting between the clubs was a League Cup tie at Somerton Park in 1962, City edging a 2-1 victory. in South Wales.
The Blues will not underestimate The Exiles who have now seen off Championship promotion chasers Middlesbrough, Premier League Leicester City, National League Wrexham and Metropolitan Police in the First Round.
Rodney Parade’s capacity is 7,850 and ticket details will be released in due course.
The match, which will be played on 16 February at 5.30pm, will be screened live on BT Sport 2.