Red Star did pull two goals back to narrow the deficit, but substitute Jaden Heskey then added to our tally as City made the ideal start to our Group G mission.
With City seeking to emulate last season’s superb group stage exploits, the game kicked off amidst driving rain and a stiff gale.
It made for testing conditions even at this early stage of the season.
Red Star enjoyed the advantage of the wind at their backs in the first half but it was City who created the first opening on three minutes.
Justin Oboavwoduo’s fine through ball set Farid Alfa-Ruphrect through as he cut in from the right flank only for Red Star keeper Marinkovic to come out and block the City winger’s shot.
And City had a gilt-edged chance on nine minutes when a sublime Max Alleyne pass set Tom Galvez free on the left flank.
The Finnish international pinged in an inviting ball into the heart of the box but Will Dickson was unable to supply the finish from 10 yards out.
Barry-Murphy’s side were dominating territory and possession, but Red Star proved resolute and a danger on the break with the contest a game of patience.
City keeper True Grant needed to be alert to dive low and smother a goal bound 34th minute shot from Red Star striker Jovan Mijatovic.
Galvez then skewed an 18-yard effort high and wide at the other end as the tempo increased.
Finally, the breakthrough arrived on 42 minutes and it deservedly went our way.
Having regained possession inside the City half, Kane Taylor motored forward before splitting the Red Star defence with a superb through ball and Emilio Lawrence needed no second invitation to latch onto the pass before slipping a shot past the advancing Marinkovic.
It was the perfect present a day before his 18th birthday.
And the day got even better for the teenager two minutes after the restart as City roared out of the blocks with a three goal blast inside seven minutes.
Receiving the ball out wide, Lawrence cut inside before firing a stunning 47th minute right footed shot into the top corner of the net for a quite brilliant strike.
And it got even better for City two minutes later as Dickson further extended our lead with a smart swivel and shot in the centre of the box after Marinkovic had somehow denied Taylor.
With our tails up City then struck again on 55 minutes as Kane Taylor fired home direct from a corner kick.
Red Star though sought to try and repair the damage and claimed their first goal on 57 minutes as the dangerous Mijatovic fired home via a deflection.
City remained on the front foot though and Marinkovic produced three stunning saves in succession to deny Oboavwoduo, Alfa-Ruprecht and Samuel.
Red Star though kept pressing and gained another goal on 78 minutes through substitute Mateja Bunaji after True Grant had made a fine initial save.
City though pressed again and restored our three goal advantage on 82 minutes after more Lawrence trickery set up substitute Jaden Heskey for a smart close range finish.
Overall however, it was impressive stuff from the City youngsters and an encouraging glimpse into the huge potential within the squad.
How we lined up
CITY XI: Grant, Samuel (Carrington 88), Simpson-Pusey, Alleyne, Galvez (Wright 88), Susoho, Alfa-Ruprecht (Heskey 75), Oboavwoduo, Dickson, Taylor, Lawrence (Warhurst 88)
RED STAR: Marinkovic, Nedeljković, Stojsavljević, Milosavljević, Vukičević, Šljivić, Petrović, Mijatović, Lečić, Maksimović, Vukojević
What it means
Brian Barry-Murphy’s side open our European campaign with a deserved three point haul.
City return to UEFA Youth League early next month when we travel to tackle RB Leipzig Under-19s on Wednesday, 4 October, with kick-off scheduled for 13:00pm (UK).
The City youngsters make a swift return to action on Friday when we play host to Chelsea at the Joie Stadium in a key PL2 fixture.
The action gets underway at 19:00 (UK) and the match will be screened live on CITY+.