A late Ellen White strike earned City, who had been reduced to ten inside 35 minutes, a share of the spoils courtesy of a 2-2 draw at the Leigh Sports Village.
Gareth Taylor's side were on top in the early stages of the game before Georgia Stanway, deputising at right back, was shown a straight red for a high challenge on Leah Galton.
But City rallied from that setback and found ourselves in front before the break when Khadija 'Bunny' Shaw headed home Demi Stokes' inch-perfect cross from the left.
We weathered the United storm until the 73rd minute, when a short corner routine caught the City defence off guard, allowing substitute Lucy Staniforth to flick home the equaliser.
And things went from bad to worse soon after, Alessia Russo afforded too much space inside the area to fire a low drive past the despairing dive of Karima Taeib with 15 still to play.
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Once again, however, Gareth Taylor's side responded defiantly, and substitute White was on hand to pounce after Jess Park's stinging long-range drive had been tipped onto the bar by Mary Earps.
Enjoy the best of the action from a thrilling Manchester Derby via the video above...