Graham Potter's side have enjoyed a fine start to the 2021/22 Premier League campaign, sitting fourth in the table with four wins and three draws from their opening eight games.
City's last visit to the AMEX Stadium saw the south-coast outfit snatch a 3-2 win, having come from 2-0 down in a dramatic, topsy-turvy encounter but Guardiola asserts there is no desire for revenge.
"I enjoy watching Brighton," he said. "They are an exceptional team.
"They are the same team [as last season. We are] absolutely not [looking for revenge]. In football, you win or lose.
"Last season, we were Champions. We were preparing to play the Final of the Champions League. Now, we are fighting to be Champions - there is a big difference."
Live text updates will begin in our Matchday Centre at 15:30, whilst our Matchday Live show gets under way one hour before kick-off, with Michael Brown and Paul Dickov this week’s guests.
A match report and all the reaction from Guardiola and a player will be available shortly after the full-time whistle, with highlights free to watch from 21:15.
CITY+ subscribers can watch a full 90-minute replay of the match from midnight.