And once again set to take centre stage for the Red Devils will be midfield maestro Kevin De Bruyne.
This is the third World Cup where De Bruyne has been a key figure in Belgium's squad and, in 2018, he helped Roberto Martinez's squad to the semi-finals - the country's best-ever showing.
The Belgium boss knows he can totally rely on the City inspiration given his talismanic role over many years at the Etihad Stadium.
In our latest World Cup showreel, we highlight some of the key contributions KDB has made in a sky blue shirt.
Stunning goals, quite brilliant assists and quality and consistency of the highest order have marked De Bruyne as a true, all-time City great.
Watch the video above to see some of Kevin's most memorable highlights in a City shirt...