City travelled to the south coast looking to further cut the gap at the top to Chelsea - standing in their way was second-placed Southampton.
It was expected to be a tricky test, but the Blues showed their class, sweeping the hosts aside after the break
First Yaya Toure scored before City were reduced to 10 men as Eliaquim Mangala was shown a second yellow card on 74 minutes.
But Frank Lampard (80) and the Gael Clichy (87) rounded off an impressive 3-0 win that enabled the Blues to leapfrog the Saints into second spot.
Watch the goal again above...