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With the memory of the 5-0 win against the Hammers still fresh, City could be forgiven for thinking this meeting would be a much more closely contested affair.
Since then, the Hammers have improved markedly and the Dimitri Payet controversy has finally ended.
Yet there’s something about the London Stadium the Blues thoroughly enjoy – the pitch is bigger than the majority of Premier League clubs and City have the players to exploit the extra space.
Pep Guardiola made three changes from the side that beat Crystal Palace 3-0 at the weekend, but the youthful front three of Gabriel Jesus, Leroy Sane and Raheem Sterling retained their places.