Nathan Ake, who suffered the loss of his father earlier this week, retains his place having scored in the 6-3 win over RB Leipzig on Wednesday, but Kevin De Bruyne, Ferran Torres and Riyad Mahrez all drop to the bench.
SOUTHAMPTON: McCarthy, Walker-Peters, Stephens, Romeu, Ward-Prowse (C), Armstrong, Adams, Redmond, Livramento, Elyounoussi, Bednarek
SUBS: Forster, Lyanco, Perraud, Broja, Djenepo, Salisu, Tella, Diallo, Valery.
It looks as if Guardiola will continue with the 4-3-3 system which has been so successful in recent weeks.
The big question before kick-off is, who will lead the forward line in place of Torres? Will Sterling be a like for like replacement or will Jesus return to a central position after proving so effective out wide?
MATCH STATS AND FACTS
- City have won eight of the past nine Premier League meetings, with the exception a 1-0 defeat at St Mary's in July 2020.
- Southampton have gone 10 league games without a win away to City, losing nine of those fixtures.
- Guardiola has won 219 at City. Should he win today, he equals Les McDowell's record of the most victories as manager.
- City could become the third team in top-flight history to win four consecutive home games by at least a five-goal margin, emulating Aston Villa in 1899 and Everton in 1931.
- We have scored 21 goals in our past four home matches in all competitions, with 13 different players on target, plus two own goals.
- None of our previous 47 league and cup matches has ended in a draw (W39, L8). We last drew against West Brom on 15 December.
- Raheem Sterling is making his 200th Premier League appearance for City. He is three shy of 100 Premier League career goals, including 18 for Liverpool.
- Sterling has been directly involved in 11 top-flight goals against Southampton, scoring seven and assisting four.