Pep Guardiola's men make the journey to Merseyside on Sunday 16 October, with kick-off scheduled for 16:30 (UK).
City remain unbeaten in the Premier League this season, winning seven of our nine matches so far.
On the other hand, the hosts have endured a slow start to the campaign, and come into this weekend's clash searching for their first win in domestic competition since August.
However, after beating Rangers 7-1 in midweek, Jurgen Klopp's side are not to be taken lightly.
City and Liverpool served up a thrilling title race across 2021/22, with each of last year's encounters among some of the most exciting matches across the Premier League season.
Everything points towards a similarly exciting showdown this weekend, leaving FPL managers with plenty of potential game winners at their disposal.
With this week's transfer deadline coming at 18:30 (UK) on Friday, you can find the Scout's latest report below...
A rested Bernardo Silva (£7.0m) could prove a key player for Manchester City in Gameweek 11 of Fantasy Premier League.
The Portuguese made a late, second-half appearance as a substitute against FC Copenhagen in the UEFA Champions League in midweek.
That suggests he is set to return to the champions’ starting XI away to Liverpool this Sunday afternoon.
Bernardo visits Anfield in consistent form in Fantasy.
Since making his first start of the season in Gameweek 3, he has produced two goals, four assists and 45 points.
The underlying numbers also back up the 28-year-old’s influence on the City attack.
Bernardo’s seven shots in the box and 14 chances created from Gameweek 3 onwards both rank among the top three players for Pep Guardiola’s side.
Opponent to watch
Meanwhile, Mohamed Salah (£12.7m) looks back to his best for Liverpool after scoring a hat-trick in Europe in midweek.
The Egyptian averages 8.4 points per home match against City, with
four goals, two assists and only one blank in those five outings.
Fantasy managers on the lookout for differentials should consider Patson Daka (£5.7m) and Gianluca Scamacca (£6.8m), who are both owned by no more than 2.0 per cent.
Leicester City’s Daka hosts Crystal Palace on the back of three goals and an assist in his last four outings.
Scamacca has scored in four of West Ham United’s last six matches in all competitions ahead of a visit to Southampton.