When and where
City travel to Anfield on Wednesday 4 April, kick-off at 7:45pm (BST).
In the UK, the game will be shown live via BT Sport 2 but for those who can’t watch the game, don’t worry as we'll have live radio commentary right here on mancity.com, while you can also get live updates on the City Matchday App and Twitter.
Pep Guardiola confirmed that Sergio Aguero hadn't travelled to Liverpool with the team due to an ongoing knee problem, while the boss stated that Fabian Delph was back in contention.
Benjamin Mendy is closing on a return from a long-term knee injury.
READ: Team injury news
Liverpool's Emre Can (back) missed Saturday's league clash with Crystal Palace.
Joel Matip looks set to miss the rest of the season with a thigh injury while Klopp has cofirms that Adam Lallana will be out for a number of weeks.
The Reds boss also stated during his recent press conference that Nathaniel Clyne is in contention for Wednesday's match.
City and Liverpool have produced two thrilling Premier League encounters this season - the Blues triumphing 5-0 in September, before the Reds edged a seven-goal thriller in January.
Word from the opposition
"For those who have seen our two clashes in the Premier League this year, and in the last few years as well since Pep arrived - and, to be honest, before his era - they know that it's always an exciting match. And that's the way football should be," Jurgen Klopp said ahead of the match.
"The main focus probably won't be on the result, instead it'll be about doing more things right than the opponent, because you can't simply defend against Man City and hope that they won't score on the day. They're just too good."
- The two teams have never met before in UEFA competition
- City have emerged victorious in 45 of the meetings between the two sides, drawing 46, with Liverpool winning 87
- The tie will see Raheem Sterling and James Milner face their former sides