That win set up a date with Watford in the final in May – and with the Carabao Cup already in the bag and City very much in contention to win the Premier League and Champions League, an unprecedented Quadruple remains a possibility.
City have already played 51 games this season - a figure that will rise to 63 if everything goes to plan for the remainder of the campaign.
And De Bruyne says City’s packed schedule means he cannot look too far ahead.
“No, the schedule is too busy!” he said. “How can you think about what is gonna happen at the end of the season if you play every three days?
“We already have a disadvantage because, like this week, we have to play Tuesday, Tottenham played their last game on Wednesday and we played on Saturday.
“We just have to take it how it is and that’s it.”
Meanwhile, De Bruyne says the City players should not fear the atmosphere inside Tottenham’s new stadium.
The two teams meet in the Champions League quarter-final on Tuesday in what will be the first European match played at the Tottenham Hotspur Stadium since its grand unveiling last week.
The opening match at the new site saw them beat Crystal Palace in front of a raucous crowd – but De Bruyne says it will be nothing unusual for the City players.
“I don’t think there’s any difference if we play at Wembley or there [Tottenham Hotspur Stadium],” he said.
“Maybe they [the fans] are a little bit more excited because they can play at their new home but in the end it’s the same.
“The stadium is going to be 60,000 people there for Tottenham. It’s the same when we play at home, we have our home supporters. In the end, it’s the same.”
The win over Brighton means we have now won 22 of our last 23 games, a remarkable run that has put us in contention to make significant history.
It’s a period of form that has seen many pundits suggest the Quadruple may well be possible and got the City fans dreaming.
But De Bruyne says our previous results are insignificant, all that matters is how strongly we finish the campaign.
“There’s no point looking back at what we did do or what we didn’t do,” he said. “Every game is gonna be a tough one, every game is different challenges.
“We just take it game by game and, hopefully, go as far as possible.”
After an injury-affected season, he looks to be getting back to his best.
And the Belgian says he is happy with how he is playing.
“I feel okay, I’m doing well,” he said. “For me, I am just trying to help the team win games and hopefully go as far as possible in whatever we’re doing.”
You can follow Tuesday's game with minute-by-minute updates in our Matchday Centre!