When and where
City’s defence of the trophy gets under way at 7.45pm (BST) on Tuesday 24 September at Preston’s Deepdale stadium.
The game will not be broadcast live in the UK but you can keep up-to-date with all the action via our Matchday Centre or on Twitter: @ManCity
If you are watching from abroad, check out our TV listings to find out how you can tune in wherever you are in the world.
Aymeric Laporte (knee), John Stones (thigh) and Leroy Sane (knee) will all miss the game for City.
Centre-back and captain, Tom Clarke is out with a knee injury, while striker Louis Moult is also unavailable (ACL).
Referee: Lee Mason
Assistants: Marc Perry and Nick Hopton
Fourth official: Tony Harrington
Last time out
A scintillating display of attacking football saw City put eight past Watford without reply.
Preston come into the game in third place in the Championship and on the back of a 1-0 win away at Birmingham City.
City won 3-1 that day, with Michael Ball, Stephen Ireland and an own goal enough for the victory after David Nugent had given the hosts an early lead.