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The Premier League Champions host the Cottagers on Saturday 15 September, kick-off at 3pm (BST).
Due to its kick-off time, the clash will not be shown live in the UK but fans around the world can find out where they can watch the match with our TV listings…
Raheem Sterling (back) has been passed fit for the match
Kevin De Bruyne is out after sustaining a lateral collateral ligament (LCL) lesion in training.
Claudio Bravo is also unavailable, having sustained an Achilles tendon injury. The Chilean 'keeper underwent scans, which confirmed a rupture in the tendon of his left foot.
Tom Cairney (foot) and Tim Ream (thigh), while Neeskens Kebano (ankle) is not expected to return until the end of September.
The pair have met 63 times in all competitions.
City have triumphed on 30 occasions and Fulham 17, while there have been 16 draws.
We last faced the London outfit back in March 2014 in the Premier League.
Yaya Toure bagged a hat-trick, as City ran out 5-0 winners. Fernandinho and Martin Demichelis were also on the scoresheet.
You can remind yourself of the match with our highlights below...
“I understood when I watched them (Fulham) the reason why they are in the Premier League. They have really good players, experienced players and they try and (I like) the way they want to play.
“They want to make their own game, and I’m pretty sure Slavisa Jokanovic is going to make a good season.”
"Man City are an important football team. They have a great history and are making big steps to be competitive in all competitions. They are always available for the fight.
"We know it's not going to be easy playing at the Etihad, but it's a great chance for us. We have fought for this chance. We won't give up."
• City are unbeaten in our last 11 meetings with the Cottagers, winning eight of those encounters, including the last five in a row.
• The Blues have won 11 of the 24 Premier League meetings, while there have been nine draws.
• Both sides have a better away record in this fixture than home (five home wins and six away for City; one home win and three away for Fulham).
• Fulham's last victory over the Blues arrived in April 2009 - a 3-1 triumph at the Etihad Stadium.
Patrick Roberts, Andy Cole, Seko Fofana, Dickson Etuhu, Michael Brown