The City boss reaffirmed the view that won’t play for up to six weeks, which would take him up to the start of January.
“John will be out for up to six weeks,” said the Blues’ boss.
“All of the month he will be out but hopefully he will recover well for start of January.”
Stones left the pitch against Leicester with a suspected hamstring injury and was replaced by with 31 minutes played.
“We don’t have a big squad,” continued the manager. “We lost Vincent Kompany in an international game and now, John Stones.
“It is not easy to play 12 games in a short space of time. I will like seeing how we will react - how players will play in different positions than they are used to playing. Tough situations.
“When things are comfortable, that is not a lot of credit. I want to see how we will react.
“Maybe Tosin Adarabioyo is another option. We will see. It depends on the players. We have Tosin, Brahim and Phil training will us from the beginning of the season.
“They have a chance to play, of course.”
With top spot in Group F still to be decided, Pep added he will select a side that he believes can win the game and all-but secure pole position in the Round of 16.
“The first step we have done. We are already qualified, but for the draw for the last 16, you never know. It is better to play the second leg at home
“I will prepare and the players will prepare to win the game. The Champions League is a prestigious competition. If we are able two in, we are going to do that.”